Avandia, a Drug for Diabetes, Another Vioxx?
Reminiscent of Vioxx, which Merck pulled off the market in 2004 after it was shown to cause heart attacks in some patients, an analysis to be published in the New England Journal of Medicine found that Avandia, a widely used pill to treat adult-onset, or Type 2, diabetes, raises the risk of heart attack by 43 percent. Over a seven-year period, taking Avendia raises the chance of a diabetic having a heart attack from 20.2 to 28.8 percent, meaning that possibly tens of thousands of people had heart attacks as a result of taking the medication. The U.S. Food and Drug Administration has advised that patients not discontinue taking Avandia on their own, but that they first discuss the situation with their doctor. Of particular concern is that for six months the F.D.A. has known of the increased cardiac risk, which was reported in an analysis submitted to it by the manufacturer of Avandia, GlaxoSmithKline. Questions have been raised as to why diabetics and their doctors have not